Epstein–Barr Virus Mucocutaneous Ulcer: An Unexpected Diagnosis of a New Entity

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center">EBV +ve DLBCL</td><td class="align_center">EBVMCU</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Population</td><td class="align_center">Usually elderly patients</td><td class="align_center">Usually age-related immune somnolence or young patients with iatrogenic immunosuppression</td></tr><tr><td class="align_left">Macroscopic</td><td class="align_center">Usually associated with mass lesion</td><td class="align_center">Sharply demarcated ulcers</td></tr><tr><td class="align_left" rowspan="3">Histopathology</td><td class="align_center">Mixed inflammatory infiltrate of lymphocytes, plasma cells, histiocytes, and eosinophils</td><td class="align_center">Mixed inflammatory infiltrate of lymphocytes, plasma cells, histiocytes, and eosinophils</td></tr><tr><td class="align_center">EBV +ve large cells only</td><td class="align_center">Band of small T cells at the base of ulcer</td></tr><tr><td class="align_center"> </td><td class="align_center">EBV +ve in variety of cell sizes</td></tr><tr><td class="align_left">Growth</td><td class="align_center">Aggressive</td><td class="align_center">Limited</td></tr><tr><td class="align_left">Prognosis</td><td class="align_center">Poor</td><td class="align_center">Favourable</td></tr><tr><td class="align_left">Treatment</td><td class="align_center">Chemoradiotherapy, surgical</td><td class="align_center">Usually conservative</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Differentiating characteristics of EBV +ve DLBCL and EBVMCU.</div>

Case Reports in Otolaryngology

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Table 1: Epstein–Barr Virus Mucocutaneous Ulcer: An Unexpected Diagnosis of a New Entity 